Mucormycosis And Hemophagocytosis Syndrome in A Patient Following Acute Myeloid Leukemia

Abstract

Acute Myeloid Leukemia (AML) is a malignant disease that affects the bone marrow and may affect red blood cells, white blood cells(myeloblasts), and platelets. Some cases of disease may be asymptomatic and can be diagnosed from random blood tests. AML mostly affects cells that are not fully developed, causing these cells to fail to perform their normal functions. If this disease is left untreated, it gets worse quickly and can be fatal. Genetic factors may cause the development of AML, but the exact cause is not known. There are environmental factors in AML etıology (eg, chemicals, radiation, tobacco, chemotherapy), in some patients, AML may occur due to  clonal hematopoiesis manifest as a myelodysplastic syndrome, myeloproliferative neoplasms, paroxysmal nocturnal hemoglobinuria, aplastic anemia and more. Here we present a case report of 59 years old male patient presenting to the clinic with malaise and referred to haematology department due to pancytopenia. However, further investigations confirmed AML.