Use of Omeprazole in A Junction to Band-Ligation for Portal Hypertensive Patients in Al-Managel Hospital 2024, Sudan
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Abstract
Portal hypertensive patients candidate for Band ligation were administered Omeprazole tab (proton pump Inhibitor) in Al-Managel Hospital to assess post-ligation ulcer healing and Heartburn, dysphagia and odynophagia Symptoms following ligation. Forty-five patients were treated with Omeprazole tab 20 mg twice daily for one week immediately after the ligation session and rechecked in the next session (3-4) weeks later. Healing of post-banding ulcers occurs naturally without significant association with using Omeprazole, as examined by Qui Square and Fisher's exact test. Omeprazole is significantly associated with decreased heartburn and odynophagia symptoms as checked by an Independent Paired T-test. Adjunctive use of Omeprazole with Band ligation for Portal Hypertensive patients is recommended to improve post-ligation symptoms of heartburn and odynophagia.
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