Lion’s Mane Mushroom- From Culinary to Medicine
Article Sidebar
Main Article Content
Abstract
Lion's Mane, a distinctive mushroom found across the Northern Hemisphere, has captivated the world with its unique appearance and potential health benefits. This article explores the diverse facets of Lion's Mane, from its taxonomy and habitat to its rich nutritional composition, including proteins, carbohydrates, fats, vitamins, minerals, and an array of biologically active compounds, notably polysaccharides and phenolic compounds. Lion's Mane is emerging as a potent dietary supplement, with research highlighting its positive impact on brain health, nerve recovery, mood stabilization, gastric health, heart health, blood sugar regulation, cancer prevention, and immunity enhancement. While Lion's Mane offers promising health benefits, it is essential to recognize its role as a complementary dietary addition rather than a substitute for medical treatments. Fortunately, Lion's Mane is generally considered safe for prolonged consumption, with minimal reported side effects. As research continues to unveil the multifaceted potential of the Lion's Mane, it stands as a fascinating and versatile natural resource with the promise of contributing to improved well-being and longevity.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
References
Lower Fungi & Higher Fungi [Internet]. Plantlet. 2020 [cited 2021 Aug 25]. Available from: https://plantlet.org/lower-fungi-higher-fungi/.
Blackwell M. The Fungi: 1, 2, 3 … 5.1 million species? American Journal of Botany. 2011;98:426–438.
Thongbai B, Rapior S, Hyde KD, et al. Hericium erinaceus, an amazing medicinal mushroom. Mycol Progress. 2015;14:91.
Friedman M. Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans. Foods. 2016;5:80.
Protected UK Fungi [Internet]. Wild Food UK. [cited 2021 Aug 25]. Available from: https://www.wildfooduk.com/protected-uk-fungi/.
Niego AG, Rapior S, Thongklang N, et al. Macrofungi as a Nutraceutical Source: Promising Bioactive Compounds and Market Value. J Fungi (Basel). 2021;7:397.
Sokół S, Golak-Siwulska I, Sobieralski K, et al. Biology, cultivation, and medicinal functions of the mushroom Hericium erinaceum. 2016;18.
Asim Shah Bacha S, Ali S, Ye L, et al. Lion’s mane mushroom; new addition to food and natural bounty for human wellness: A review. 2018;
Cohen N, Cohen J, Asatiani M, et al. Chemical Composition and Nutritional and Medicinal Value of Fruit Bodies and Submerged Cultured Mycelia of Culinary-Medicinal Higher Basidiomycetes Mushrooms. International journal of medicinal mushrooms. 2014;16:273–291.
Friedman M. Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion’s Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds. J Agric Food Chem. 2015;63:7108–7123.
Can dementia be prevented [Internet]. nhs.uk. 2017 [cited 2021 Aug 29]. Available from: https://www.nhs.uk/conditions/dementia/dementia-prevention/.
Nkodo A. A Systematic Review of in-vivo Studies on Dietary Mushroom Supplementation for Cognitive Impairment (P14-021-19). Current Developments in Nutrition [Internet]. 2019 [cited 2021 Aug 29];3. Available from: https://doi.org/10.1093/cdn/nzz052.P14-021-19.
Samberkar S, Gandhi S, Naidu M, et al. Lion’s Mane, Hericium erinaceus and Tiger Milk, Lignosus rhinocerotis (Higher Basidi-omycetes) Medicinal Mushrooms Stimulate Neurite Outgrowth in Dissociated Cells of Brain, Spinal Cord, and Retina: An In Vitro Study. IJM [Internet]. 2015 [cited 2021 Aug 29];17. Available from: https://www.dl.begellhouse.com/journals/708ae68d64b17c52,343363596ed9bda8,45484d446fc46878.html.
Lai P-L, Naidu M, Sabaratnam V, et al. Neurotrophic Properties of the Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. IJM [Internet]. 2013 [cited 2020 Dec 13];15. Available from: http://www.dl.begellhouse.com/journals/708ae68d64b17c52,034eeb045436a171,750a15ad12ae25e9.html.
Rossi P, Cesaroni V, Brandalise F, et al. Dietary Supplementation of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), and Spatial Memory in Wild-Type Mice. IJM [Internet]. 2018 [cited 2021 Aug 29];20. Available from: https://www.dl.begellhouse.com/journals/708ae68d64b17c52,6de384366c0c5922,5af64f332e1ca306.html.
Üstün R, Aden M, Oğuz EK, et al. Healing effect of Hericium erinaceus in experimental peripheral neuropathy model. Anatomy: International Journal of Experimental & Clinical Anatomy. 2019;13.
Wong K-H, Naidu M, David RP, et al. Neuroregenerative Potential of Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Higher Basidiomycetes), in the Treatment of Peripheral Nerve Injury (Review). IJM [Internet]. 2012 [cited 2020 Dec 13];14. Available from: http://www.dl.begellhouse.com/journals/708ae68d64b17c52,03ea8c440cfbb276,23c2fd3840f4e0c9.html.
Nagano M, Shimizu K, Kondo R, et al. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomedical Research. 2010;31:231–237.
Chong PS, Fung M-L, Wong KH, et al. Therapeutic Potential of Hericium erinaceus for Depressive Disorder. International Journal of Molecular Sciences. 2020;21:163.
Ryu S, Kim HG, Kim JY, et al. Hericium erinaceus Extract Reduces Anxiety and Depressive Behaviors by Promoting Hippocampal Neurogenesis in the Adult Mouse Brain. Journal of Medicinal Food. 2018;21:174–180.
Wang M, Konishi T, Gao Y, et al. Anti-Gastric Ulcer Activity of Polysaccharide Fraction Isolated from Mycelium Culture of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes). IJM [Internet]. 2015 [cited 2021 Aug 29];17. Available from: https://www.dl.begellhouse.com/journals/708ae68d64b17c52,343363596ed9bda8,006faf937d2f02af.html.
Wong J-Y, Abdulla MA, Raman J, et al. Gastroprotective Effects of Lion’s Mane Mushroom Hericium erinaceus (Bull.:Fr.) Pers. (Aphyllophoromycetideae) Extract against Ethanol-Induced Ulcer in Rats. Evidence-Based Complementary and Alternative Medicine. 2013;2013:e492976.
Wang G, Zhang X, Maier SE, et al. In Vitro and In Vivo Inhibition of Helicobacter pylori by Ethanolic Extracts of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes). IJM [Internet]. 2019 [cited 2021 Aug 29];21. Available from: https://www.dl.begellhouse.com/journals/708ae68d64b17c52,2806f82d786f0ca1,6e9ef24864bd9e52.html.
Jang HS, Yoon KN. The Antihyperlipidemic Effect of Lion’s Mane Mushroom (Hericium erinaceus) in Hyperlipidemic Rats Induced by High Fat and Cholesterol Diet. Korean Journal of Clinical Laboratory Science. 2017;49:263–270.
Rahman MA, Abdullah N, Aminudin N. Inhibitory Effect on In Vitro LDL Oxidation and HMG Co-A Reductase Activity of the Liquid-Liquid Partitioned Fractions of Hericium erinaceus (Bull.) Persoon (Lion’s Mane Mushroom). BioMed Research Interna-tional. 2014;2014:e828149.
Lee SK, Ryu SH, Turk A, et al. Characterization of α-glucosidase inhibitory constituents of the fruiting body of lion’s mane mushroom (Hericium erinaceus). Journal of Ethnopharmacology. 2020;262:113197.
Yao F, Gao H, Yin C-M, et al. Evaluation of In Vitro Antioxidant and Antihyperglycemic Activities of Extracts from the Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes). IJM [Internet]. 2021 [cited 2021 Aug 29];23. Available from: https://www.dl.begellhouse.com/journals/708ae68d64b17c52,106de03537ad1f8b,23345f3277bdbd98.html.
Li W, Zhou W, Kim E-J, et al. Isolation and identification of aromatic compounds in Lion’s Mane Mushroom and their anticancer activities. Food Chemistry. 2015;170:336–342.
Kim SP, Nam SH, Friedman M. Hericium erinaceus (Lion’s Mane) Mushroom Extracts Inhibit Metastasis of Cancer Cells to the Lung in CT-26 Colon Cancer-Tansplanted Mice. J Agric Food Chem. 2013;61:4898–4904.
Atay S, Ak H, Kalmis E, et al. Transcriptome-Wide Analysis Reveals the Molecular Mechanism of Tumoricidal Effects of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), on MCF-7 Breast Cancer Cells. IJM [Internet]. 2021 [cited 2021 Aug 29];23. Available from: https://www.dl.begellhouse.com/journals/708ae68d64b17c52,367ee73d7a1caab0,3d4c5fa53a165c60.html.
Meena B, Sivakumar V, Praneetha S, et al. Mushroom as Potential Immunity Enhancer. Biotica Research Today. 2020;2:815–818.
Jiang S, Liu S, Qin M. Effects of Extraction Conditions on Crude Polysaccharides and Antioxidant Activities of the Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes). IJM [Internet]. 2019 [cited 2021 Aug 29];21. Available from: https://www.dl.begellhouse.com/journals/708ae68d64b17c52,296de7d03f5361dd,7795280645a5e6b3.html.
Qin M, Geng Y, Lu Z, et al. Anti-Inflammatory Effects of Ethanol Extract of Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), in Mice with Ulcerative Colitis. IJM [Internet]. 2016 [cited 2021 Aug 29];18. Available from: https://www.dl.begellhouse.com/journals/708ae68d64b17c52,23ce65314f371f4f,5d11b27c03b8f781.html.
Lee L-Y, Li I-C, Chen W-P, et al. Thirteen-Week Oral Toxicity Evaluation of Erinacine AEnriched Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), Mycelia in Sprague-Dawley Rats. IJM [Internet]. 2019 [cited 2020 Dec 13];21. Available from: http://www.dl.begellhouse.com/journals/708ae68d64b17c52,2b9ba90674ebcc50,4e14c4e165f20b4a.html.